Map
From New York, New Jersey and points south and west, take I-95 north. The River Valley begins in Branford, at exit 55.
From Providence, Mystic, Boston and points east and north, take I-95 south. The River Valley begins in Old Saybrook, at exit 69.
From western and central Massachusetts, Vermont and points north, take I-91 south. Pick up CT Route 9 south for the eastern side of the Valley, and stay on I-91 for the western side.
To reach the towns within in the River Valley and Shoreline, there are three different main routes, I-95, CT I-91 and CT Route 9.